Sodium reabsorbing epithelia play a big function in whole-body sodium homeostasis. a few examples of sodium regulating tissues comprise kidney, colon, lung, and sweat ducts. Sodium shipping throughout those membranes is a two-step technique: access via an amiloride-sensitive sodium channel and go out through the ouabain-sensitive sodium/potassium ATPase. The sodium access channels are the rate-limiting determinant for shipping and are regulated via a number of diverse hormones. The sodium channels additionally play an important function in a couple of disorder states, like high blood pressure, edema, drug-induced hyperkalemia, and cystic fibrosis. Amiloride-Sensitive Sodium Channels: body structure and useful Diversity presents the 1st in-depth trade of principles bearing on those sodium channels, their law and involvement in basic and pathophysiological occasions.
* Summarizes present kingdom of amiloride-sensitive sodium channel field
* Analyzes structure-function of epithelial sodium channels
* Discusses immunolocalization of epithelial sodium channels
* Examines hormonal legislation of sodium channels
* Discusses sodium channels in lymphocytes, kidney, and lung
* Considers mechanosensitivity of sodium channels
* presents rules on sodium channels and illness
Read Online or Download Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity, Volume 47 (Current Topics in Membranes) PDF
Similar Basic Sciences books
The main authoritative histology textual content to be had -- now in full-color A Doody's center identify crucial buy for 2011! For greater than 3 many years, Junqueira's uncomplicated Histology has been unequalled in its skill to provide an explanation for the functionality of phone and tissue constitution within the human physique. up to date to mirror the most recent examine within the box, and better with greater than 1,000 illustrations, so much in full-color, the twelfth version is the main entire and smooth method of knowing clinical histology to be had at any place.
A full-color, case-based evaluation of the necessities of pathophysiology--covering all significant organs and platforms The objective of this relied on textual content is to introduce you to medical drugs by means of reviewing the pathophysiologic foundation of a hundred and twenty ailments (and linked symptoms) normally encountered in scientific perform.
A vintage nephrology reference for over 25years, Seldin & Giebisch’s The Kidney, is the said authority on renal body structure and pathophysiology. during this fifth variation, such new and strong disciplines as genetics and mobilephone biology were deployed to deepen and widen additional the explanatory framework.
The historical past of high-altitude body structure and drugs is any such wealthy and colourful subject that it really is fabulous nobody has undertaken a complete account ahead of. From the early balloonists to numerous high-altitude expeditions, culminating within the nice feat of mountaineering Mount Everest with no supplementary oxygen, the elemental organic problem of hypoxia has underpinned the human adventure at excessive altitude.
Extra resources for Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity, Volume 47 (Current Topics in Membranes)